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PRP for Infertility Support

PRP for Infertility Support

Twelve percent of women of childbearing age in the U.S. have difficulty getting or staying pregnant.1 With more women delaying childbirth until later in life, ovarian insufficiency has become a rising problem.

Infertility can present emotional, mental, and financial challenges both for the patient and her partner. The challenge for the physician is helping the patient find safe and effective treatment options with minimal invasiveness and side effects.

The current options for achieving fertility in women with ovarian insufficiency include:

  • Synthetic hormone treatment
  • In vitro fertilization using donor eggs

However, many women aren’t comfortable with the side effects of hormone treatment which include increased risk of cardiovascular disease and breast cancer.2 Many women are also unable to afford the expense of in vitro fertilization or are uncomfortable with the necessity of using donor eggs.

Ovarian rejuvenation through platelet-rich plasma (PRP) is showing promise as a safe and effective therapy to support fertility.3

Regenerative Medicine in Fertility Treatments Webinar

  • Dr. Stephan Gordts - Gynaecologist - Life Expert Center
  • Dr. Rudi Campo - Fertility expert - Life Expert Center
  • Sonia Herraiz, PH.D. - Ovarian Rejuvenation and Fertility Preservation
  • Lucía De Miguel Gómez, PD.D. Student - at IVI RMA GLOBAL
  • Dr. Anita Van Domselaar - Co-Founder Benorm, Regenerative Medicine Specialist, Certified Interventional Pain Sonologist, Anesthetist, Life Expert Center

Platelet-Rich Plasma to Treat Infertility

Platelet-rich plasma, or PRP, is gaining traction as an alternative treatment option for infertility. PRP may use the body’s own natural healing process to help regenerate damaged ovarian tissue.

But how does it work? PRP stimulates the body’s innate healing cascade. When we experience an injury, our body responds by delivering a rush of platelet cells. When these platelets are activated, they release several types of growth factors, proteins, and cytokines that play a fundamental role in cell regeneration and tissue healing.

But PRP takes the natural healing response one step further by separating platelets from other blood components and concentrating them. This specially prepared platelet-rich plasma contains 5 to 10 times the concentration of platelets found in whole blood. The concentrated PRP is then delivered into the ovaries via injection using an ultrasound-guided or laparoscopic-assisted approach.4 The delivery of the concentrated platelet-rich plasma stimulates and significantly strengthens the body’s healing response within the ovaries.5

Intraovarian PRP injection has been shown to aid a menopausal woman in becoming pregnant.6 Ovarian PRP treatment also may have helped restore menstruation in three women who hadn’t had a menstrual cycle in over a year. These women also achieved pregnancy via natural conception within a year after PRP treatment. The women also showed:

  • Improved hormonal profile
  • Decreased follicle-stimulating hormone (FSH) levels
  • Increased anti-Müllerian hormone (AMH) levels7

Since PRP is an autologous therapy, using the patient’s own blood product, there is no risk of cross reactivity or immune reaction.

THE PRP PROCESS

To create a platelet-rich plasma preparation, the following steps are performed:

  1. A small sample of blood is drawn from the patient and injected into the Dr. PRP blood tube.
  2. The platelets are then separated from the other blood components and their concentration is increased using the Dr. PRP centrifuge and removing some of the plasma.
  3. The resulting platelet-rich plasma is then injected into and around the affected areas of concern..
  4. The concentrated growth factors contained in the plasma trigger a mild inflammatory response which effectively jump starts the body’s own natural healing response.

The entire process takes approximately one hour, including preparation and recovery time. For a complete demonstration of each step of the process, view our instructional video.

DR. PRP

The Dr. PRP is an FDA-registered medical device designed to quickly and efficiently prepare patients’ blood for PRP therapy.

Our patented design creates high-concentration and high-quality platelet-rich plasma that can be used as the physician deems necessary. This can result in tissue regeneration at the injured or diminished site, effectively accelerating normal healing processes.

REACH OUT TO LEARN MORE

BENEFITS OF DR. PRP

SAFETY

  • Completely closed, sterile system.
  • Outside air is blocked with a double safety cap.
  • Since the processing is completed within the closed system, there is no risk of the PRP becoming contaminated.

EASY TO USE

  • Each kit comes pre-packaged.
  • The clear chambers ensure that you can see all the components of the blood sample.
  • The buffy coat layer is easily seen in the neck of the device, allowing for precise separation of the components into the type of PRP desired.
  • Red Blood Cells can even be eliminated from the final PRP product.

QUICK AND CONVENIENT

  • The closed system allows for more treatments in less time.
  • Customize your final PRP composition for use in different situations.
  • The PRP can and should be administered as soon as it is prepared with our kit – no advanced preparation is needed.

HIGH CONCENTRATION

  • One kit holds 20 cc of fluid (3 cc of anticoagulant + 17 cc of whole blood) and produces 4 or more cc of highly concentrated PRP.
  • The platelet recovery percentage of Dr. PRP is higher than the minimum recovery percentage of other similar products from our competitors.

CONSISTENT RESULTS

  • Platelets require red and white blood cells to survive long-term. Unlike gel separators that capture the platelets within the gel, our kit allows you to accurately create consistently efficient PRP at the concentrations you want.

QUALITY

  • Our kit can recover over 90% of platelets from a blood sample to produce the highest quality PRP.

FDA REGISTERED

  • The kit is registered by the US-FDA for regenerative use by healthcare providers.
  • The FDA 510K is pending approval.

PATENTED DESIGN

  • According to the ISO 13485, our kit is made with a thorough gamma-ray sterilization system.
  • Made only with biocompatibility-certification completed raw materials.

TRAINING & SUPPORT

  • One-on-one, in-service training is provided via GoToTraining, FaceTime, or zoom.
  • User Manual with photos and descriptions detail how to use your new product, as well as information on PRP and test results.
  • Enroll in our Platelet-Rich Plasma CME Certification course where you can learn cosmetic applications of PRP, including the PRP Facial and PRP Facelift.

MARKETING SYSTEM

  • Order marketing materials and educational brochures for your patients. These brochures explain various applications of PRP, such as sports medicine and hair regeneration.
  • Add your contact information and location to our Directory of PRP Providers.

To view and order Dr. PRP kits and centrifuges, visit our online store.

For questions and to discuss our products in more detail, contact us today at 844-377-7787 (DR- PRP-US).

References

  1. “Infertility FAQs” Centers for Disease Control and Prevention. Accessed 24 June 2021. https://www.cdc.gov/reproductivehealth/infertility/index.htm
  2. “Primary ovarian insufficiency” Mayo Clinic. Accessed 24 June 2021 https://www.mayoclinic.org/diseases-conditions/premature-ovarian-failure/diagnosis-treatment/drc-20354688
  3. Petryk Nataliia, Petryk Mykhailo. “Ovarian Rejuvenation Through Platelet-Rich Autologous Plasma (PRP)-a Chance to Have a Baby Without Donor Eggs, Improving the Life Quality of Women Suffering from Early Menopause Without Synthetic Hormonal Treatment.” Reproductive Sciences. 2020 Nov;27(11):1975-1982. doi: 10.1007/s43032-020-00266-8. Epub 2020 Jul 22. PMID: 32700285.
  4. Petryk Nataliia, Petryk Mykhailo. “Ovarian Rejuvenation Through Platelet-Rich Autologous Plasma (PRP)-a Chance to Have a Baby Without Donor Eggs, Improving the Life Quality of Women Suffering from Early Menopause Without Synthetic Hormonal Treatment.” Reproductive Sciences. 2020 Nov;27(11):1975-1982. doi: 10.1007/s43032-020-00266-8. Epub 2020 Jul 22. PMID: 32700285.
  5. “PRP Injections for Pain” American Academy / Association of Orthopedic Medicine. https://www.aaomed.org/Platelet-Rich-Plasma-Injections-for-Pain
  6. Konstantinos Sfakianoudis, Mara Simopoulou, Nikolaos Nitsos, Anna Rapani, Athanasios Pappas, Agni Pantou, Margarita Chronopoulou, Efthymios Deligeoroglou, Michael Koutsilieris, and Konstantinos Pantos. “Autologous Platelet-Rich Plasma Treatment Enables Pregnancy for a Woman in Premature Menopause.” Journal of Clinical Medicine. 2019 Jan; 8(1): 1. doi: 10.3390/jcm8010001. Published online 2018 Dec 20. PMID: 30577435
  7. Konstantinos Pantos, Mara Simopoulou, Agni Pantou, Anna Rapani, Petroula Tsioulou, Nikolaos Nitsos, Stephen Syrkos, Athanasios Pappas, Michael Koutsilieris, and Konstantinos Sfakianoudis. “A Case Series on Natural Conceptions Resulting in Ongoing Pregnancies in Menopausal and Prematurely Menopausal Women Following Platelet-Rich Plasma Treatment.” Cell Transplantation. 2019 Sep; 28(9-10): 1333–1340. doi: 10.1177/0963689719859539. Published online 2019 Jul 4. PMID: 31271054