PRP for Osteoporosis
Our bones are made up of living, growing tissue that changes throughout our
lifespan. Osteoporosis occurs when bone loses its density,
causing it to become brittle and weak. The loss of bone strength means those
with osteoporosis are at a very high risk of fractures.
Fortunately, platelet-rich plasma, or PRP, is a rapidly
emerging therapy that can be used to enhance bone quality in osteoporosis and
accelerate healing in osteoporotic fractures.
Data from the World Health Organization (WHO) shows that osteoporosis affects
more than 200 million people worldwide. Women in particular have a 30-40% risk
of having an osteoporotic fracture within their lifetime.1
Osteoporosis-related fractures most often occur in the hip, wrist, and
vertebrae in the spine. Preventing fractures is of utmost importance when
treating patients with osteoporosis since fractures can lead to loss of
mobility, independence, and can even cause other medical problems.
Fractures also present unique challenges to the surgeon managing the fracture.
While the osteoporotic fracture undergoes the same process of healing as a
normal fracture,
fractures in osteoporotic bone are much slower to heal than in normal
bone.
Bone Healing
Bone healing is a process with three overlapping stages:
- Inflammation
- Bone formation
- Bone resorption (remodeling)
Bone healing requires a delicate balance between these stages. Bone loss from osteoporosis occurs when bone resorption exceeds bone
formation. Osteoporotic fractures are so slow to heal because of this
reduction in bone formation – as well as the reduction in bone mineral
density inherent in osteoporosis.2
During normal bone healing, platelets deliver growth factors that stimulate
the healing activity of the bone's cells. But in osteoporosis, the balance
is already tipped away from the bone formation phase, resulting in reduced
bone formation and reduced healing.
Platelet-rich plasma, or PRP, can be used to increase the
supply of growth factors available to the bone's cells. In this way, the
platelet-rich plasma accelerates bone healing. PRP also boasts a strong safety
profile with no known adverse effects.3
But how does it work? PRP assists in bone regeneration by
stimulating the body's innate healing cascade. When we experience an
injury, our body responds by delivering a rush of platelets. When these
platelets are activated, they release several types of growth factors,
proteins, and cytokines that play a fundamental role in cell regeneration and
tissue healing.
But
PRP takes the natural healing response one step further
by separating platelets from other blood components and concentrating them.
This specially prepared platelet-rich plasma contains 5 to 10 times the
concentration of platelets found in whole blood. The concentrated PRP is then
delivered into and around the site of injury via injection, stimulating and
significantly strengthening the body's healing response.4
Recent research indicates that PRP enhances bone microarchitecture in
osteoporosis.5
Likewise, research has shown that medium-concentration PRP can effectively
enhance the healing of osteoporotic fractures when transplanted into the
fracture zone.6 And since PRP is an
autologous therapy, using the patient's own blood product, there is no
risk of cross reactivity, disease transmission, or immune reaction.
Platelet-rich plasma concentrations can be uniquely prepared to meet the needs
of the patient and the problem being treated.
THE PRP PROCESS
To create a platelet-rich plasma preparation, the following
steps are performed:
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A small sample of blood is drawn from the patient and injected into the Dr.
PRP blood tube.
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The platelets are then separated from the other blood components and their
concentration is increased using the Dr. PRP centrifuge and by removing some
of the plasma.
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The resulting platelet-rich plasma is then injected into and around the
injured site of the patient.
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The concentrated growth factors contained in the plasma trigger a mild
inflammatory response which effectively jump starts the body's own
natural healing response.
The entire process takes approximately one hour, including preparation and
recovery time. For a complete demonstration of each step of the process, view
our instructional video.
DR. PRP
The Dr. PRP is an FDA-cleared medical device, holding the esteemed 510K
clearance, meticulously designed to prepare patients' blood for PRP therapy
quickly and efficiently.
Our patented design creates high-concentration and high-quality platelet-rich
plasma that your physician can use to help stimulate the healing process. This
results in bone cell growth and tissue regeneration at the injured site.
REACH OUT TO LEARN MORE
BENEFITS OF DR. PRP
SAFETY
- Completely closed, sterile system.
- Outside air is blocked with a double safety cap.
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Since the processing is completed within the closed system, there is no risk
of the PRP becoming contaminated.
EASY TO USE
- Each kit comes pre-packaged.
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The clear chambers ensure that you can see all the components of the blood
sample.
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The buffy coat layer is easily seen in the neck of the device, allowing you
to precisely separate the components into the type of PRP you wish to
produce.
- You can even eliminate red blood cells from your final PRP product.
QUICK AND CONVENIENT
- The closed system allows for more treatments in less time.
- Customize your final PRP composition for use in different situations.
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The PRP can and should be administered as soon as you prepare it with our
kit – no advanced preparation is needed.
HIGH CONCENTRATION
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One kit holds 20 cc of fluid (3 cc of anticoagulant + 17 cc of whole blood)
and produces 4 cc of highly concentrated PRP.
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The platelet recovery percentage of Dr. PRP is higher than the minimum
recovery percentage of other similar products from our competitors.
CONSISTENT RESULTS
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Platelets require red and white blood cells to survive long-term. Unlike gel
separators that capture the platelets within the gel, our kit allows you to
accurately create consistently efficient PRP at the concentrations you want.
QUALITY
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Our kit can recover over 90% of platelets from a blood sample to produce the
highest quality PRP.
FDA 510K CLEARED
- The kit is now proudly holding the FDA 510K clearance.
PATENTED DESIGN
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According to the ISO 13485, our kit is made with a thorough gamma-ray
sterilization system.
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Made only with biocompatibility-certification completed raw materials.
TRAINING & SUPPORT
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One-on-one, in-service training is provided via GoToTraining, FaceTime, or
Zoom.
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User Manual with photos and descriptions detail how to use your new product,
as well as information on PRP and test results.
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Enroll in our
Platelet-Rich Plasma CME Certification
course where you can learn cosmetic applications of PRP, including the PRP
Facial and PRP Facelift.
MARKETING SYSTEM
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Order marketing materials and educational brochures for your patients. These
brochures explain various applications of PRP, such as sports medicine and
hair regeneration.
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Add your contact information and location to our
Directory of PRP Providers.
To view and order Dr. PRP kits and centrifuges, visit
our online store.
For questions and to discuss our products in more detail, contact us today at
844-377-7787 (DR- PRP-US).
-
Ajai Singh, Sabir Ali, Rajeshwar N Srivastava. "Platelet-rich plasma
in osteoporotic fractures: A review of literature."
Journal of Orthopedics, Traumatology and Rehabilitation. Volume
7, Issue 2 (2014): 123-138. Accessed 18 June 2021.
https://www.jotr.in/article.asp?issn=0975-7341;year=2014;volume=7;issue=2;spage=123;epage=138;aulast=Singh#ref2
-
Ajai Singh, Sabir Ali, Rajeshwar N Srivastava. "Platelet-rich plasma
in osteoporotic fractures: A review of literature."
Journal of Orthopedics, Traumatology and Rehabilitation. Volume
7, Issue 2 (2014): 123-138. Accessed 18 June 2021.
https://www.jotr.in/article.asp?issn=0975-7341;year=2014;volume=7;issue=2;spage=123;epage=138;aulast=Singh#ref2
-
Peter Everts, Kentaro Onishi, Prathap Jayaram, José Fábio
Lana, and Kenneth Mautner. "Platelet-Rich Plasma: New Performance
Understandings and Therapeutic Considerations in 2020"
International Journal of Molecular Sciences. (October 2021).
Accessed 18 June 2021.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589810/
-
"PRP Injections for Pain."
American Academy / Association of Orthopedic Medicine Accessed 18
June 2021. https://www.aaomed.org/Platelet-Rich-Plasma-Injections-for-Pain
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Bo Wei, Chengshuo Huang, Mingyan Zhao, Peng Li, Xiang Gao, Junchao Kong,
Yanru Niu, Rui Huang, Juanhua Quan, Jinsong Wei, Jiaqi Chu. "Effect
of Mesenchymal Stem Cells and Platelet-Rich Plasma on the Bone Healing of
Ovariectomized Rats." Stem Cells International (November
2016) Accessed 18 June 2021. doi: 10.1155/2016/9458396.
https://pubmed.ncbi.nlm.nih.gov/27994625/
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Linwei Chen, Xiaobo Yang, Gao Huang, Dianwen Song, Xue-Shi Ye, Huazi Xu,
Wanli Li. "Platelet-rich plasma promotes healing of osteoporotic
fractures." Orthopedics (June 2013) Accessed 18 June 2021.
doi: 10.3928/01477447-20130523-10.
https://pubmed.ncbi.nlm.nih.gov/23746028/