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Ultrasound-guided platelet-rich plasma injection for traumatic painful neuroma of brachial plexus: a case report and literature review.

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  • Authors: Zhu H, Deng Z, Xie Y, Qian G, Wang D, Xie S, Zhang Y, Yan P.
  • Published: 2025-03-17
  • Publication: Front Neurol. 2025 Mar 17;16:1546773.

Traumatic neuroma (TN) is a repair response of nerves to direct/indirect trauma or chronic inflammatory injury, commonly occurring after trauma or surgery. The authors report a rare case of a traumatic painful neuroma of the brachial plexus. Physical therapy and drug treatment failed to resolve the symptoms of allodynia and a palpable mass, which significantly reduced the patient's quality. Ultrasound-guided injection of platelet-rich plasma (PRP) has shown significant efficacy in repairing the nerve and relieving pain. However, there is a lack of research on treating TN with PRP injection. This case demonstrates that ultrasound-guided injection of PRP can alleviate neuropathic pain caused by a traumatic painful neuroma of brachial plexus and improve the upper limb function.

Keywords: brachial plexus; neuroma; neuropathic pain; platelet-rich plasma; ultrasonography; ultrasound guided injection.